Now that the James Webb Space Telescope is up and running, astronomers want to use it to spot compounds such as oxygen, methane and carbon dioxide in the atmosphere's of exoplanets – or, better yet, more than one in the same atmosphere. "If you, like, took some water and some methane and put them in a box and left them at room temperature on Earth, they'd actually combine into carbon dioxide, and you wouldn't expect there to be any methane left over," said Megan Mansfield, an astronomer at the University of Arizona who will use Webb to study exoplanets.